SP Energy Networks is reporting power cuts in north Wales, including the area around Ysbyty Gwynedd in Bangor, Bethesda, Tregarth, Llanbedr, Blaenau Ffestiniog and Menai Bridge on Anglesey
Further south, the energy supply company National Grid is reporting 29 different incidents with the worst affected areas at present at Three Cocks in Powys and Pontyates in Carmarthenshire.
Some 33 schools on Anglesey and five in Gwynedd will remain closed on Friday due to harsh weather conditions.
Several ferry services running to and from Dublin to Holyhead have been cancelled into Friday afternoon, Stena Line announced on Thursday.
In a joint statement, Transport for Wales and Network Rail asked all customers to check before they travel on Friday and into the weekend as delays and cancellations were expected.
It added that trains would not run on some lines and speed restrictions would be implemented on some locations to minimise potential disruption.
Rail operators Avanti West Coast, CrossCountry, and Grand Central have also warned customers not to travel on routes across parts of north Wales and Scotland.
Natural Resources Wales (NRW) has closed four forests and reserves on Friday due to the risk of trees damaged by previous storms falling.
Visitor centres at Coed y Brenin in Gwynedd, Bwlch Nant yr Arian and Ynyslas in Ceredigion, as well as Newborough National Nature Reserve and Forest on Anglesey, will be closed to the public.