About 6,300 people work at the sprawling NHS site, which first opened as a hospital 1905.
It is one of the largest hospitals in Greater Manchester, serving Stockport as well as parts of Cheshire and Derbyshire, but has suffered from the poor condition of some its buildings.
Demolition work has started at the outpatients B department, which shut last year after failing a safety inspection, causing a significant reduction in capacity for consultant clinics.
Tiles fell from the roof of the intensive care unit in March, forcing patients to be evacuated and taking 13 critical care beds out of action until earlier this week.
Elsewhere, a recent leak at the radiology department led to ultrasound appointments being rescheduled.
Tom Morrison, a Liberal Democrat councillor for Cheadle West and Gatley in Stockport, said he met nurses there who “referred to themselves as a bucket squad” as they had regularly put them out to catch rain from the ceiling.
