“He started to make groaning sounds. It was like he was in pain but he could not tell us he was in pain.”

Ms Woods added Mr Skripal’s presentation was “very odd” although he “remained effectively inwardly very stable”.

Dr James Haslam, a consultant in anaesthesia and intensive care medicine at Salisbury NHS Foundation Trust, cared for the Skripals from 5 March onwards.

He said Ms Skripal’s condition was “worse than her father”.

Upon arrival she was unable to breathe on her own, and was subsequently intubated and given mechanical ventilation.

When Mr Skripal arrived he was breathing for himself, but as time passed he too was unable to breathe on his own.

“We couldn’t record their temperature because it was that low, and that’s despite active warming,” he said.

The inquiry continues.

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