Productions already booked for 2024 and 2025 will not be affected by the closure, nor will TV productions taking place at other Pinewood sites.
The site offered three fully-equipped TV studios for the creation of sitcoms, panels shows and live broadcasts.
It also been used to film Red Dwarf, Would I Lie To You and Gordon Ramsey’s Future Food Stars.
Pinewood said it was consulting with staff affected by the closure.
In 2019, Disney signed a deal to lease 20 of the stages at the site, months after Netflix agreed to a similar deal at Pinewood’s Shepperton Studios.