For Bolton Hospice, where Dr Vallance works as chief executive, the impact of the NI hike will cost about £80,000, she told Radio Manchester.
“That is a significant amount of money on an already deficit budget,” she said.
It comes after contributions from the NHS have declined over the past 14 years, with the majority of the hospice’s funding generated from donations “from the people of Bolton”, Dr Vallance said.
“To ask for even more is a challenge, so the focus really needs to be on a fairer funding deal with the NHS, and on top of that, the extra £80,000.
“Because without addressing it, services will inevitably have to be curtailed.”