Network Rail said the machine derailed “at slow speed” and no-one was injured.
A spokesperson said: “We’re working closely with the operator and others to understand more about what happened.”
Routes affected include:
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Northern route between Blackpool North and Wigan North Western and Liverpool Lime Street
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Northern route between Barrow-in-Furness, Windermere and Manchester Airport,
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TransPennine Express route between Glasgow Central and Liverpool Lime Street
Replacement bus services have been put in place for some services from Wigan North Western.
National Rail posted details of alternate journeys, external on its website.
Passengers faced two weeks of delays after a train derailed near Grange-over-Sands in March.
A Northern train travelling towards Barrow, in Cumbria, came off the tracks, leading to four passengers and four members of staff being evacuated from the train.
