Linda Nolan has died, aged 65, following a two-decade long struggle with breast cancer.
The Irish singer, who rose to fame alongside her sisters in the group The Nolans, passed away on Wednesday morning, her family has confirmed.
Devastatingly, she was not the only sister to face a breast cancer diagnosis: older sister Anne, 74, and young sister Bernie, who died 2013 aged 52, also suffered the disease.
Meanwhile Coleen, 59, the youngest Nolan, suffered skin cancer in 2023 — a basal cell carcinoma on her shoulder and pre-cancerous melanoma on her face.
The Loose Women star has previously admitted checking her body for signs of cancer — a disease that has stalked their family — has become a daily ritual.
Their father, Tommy Nolan Sr, was also struck down, dying from liver cancer in 1998.
Linda, who is the third youngest of the six sisters, was first diagnosed with stage-three breast cancer in 2005 before getting the all-clear in 2006.
But in 2017 she was given the terrible news the disease had returned — there were tumors in her hip, and the cancer then spread to her liver in 2020.
And in August, Linda issued an update that the tumours in her brain – which were thought to be stable – have grown
Friends and family members have paid tribute to Linda Nolan following her death to breast cancer on Wednesday
Around 55,000 women and 370 men are diagnosed with breast cancer each year in the UK, says Breast Cancer Now
In 2023, she shared the news that two tumours had been discovered on the left side of her brain which left her struggling with her speech and balance.
And in March last year Linda, who had the HER2-positive type of breast cancer, started immunotherapy every three weeks in a bid to slow the spread.
She was also given a new breast cancer drug, Enhertu, which has helped extend the lives of women with the same diagnosis.
HER2-positive breast cancers accounts for roughly one in five cases of the disease and is an aggressive and fast-growing form.
Despite several family members also receiving cancer diagnosis, HER2-positive is not hereditary, meaning the gene mutation can’t be passed on.
Appearing on Good Morning Britain last year, Linda revealed that she was being set on a new course of chemotherapy as a result of the tumour growth — and shared the news that she could face losing her hair once again.
She also revealed the physical toll the ongoing treatment was taking on her smile, pointing to a gap in her teeth and exclaiming: ‘Look, I’ve lost a tooth!’
In an interview with the Mirror she admitted she was left ‘sobbing’ as the doctor delivered the results, saying how she wished cancer would just ‘leave her alone.’
‘I sobbed when my consultant first told me. I know so many people are suffering and going through things, but I thought, just for once, could cancer just leave me alone? My heart sank,’ she added.
Around 55,000 women and 370 men are diagnosed with breast cancer each year in the UK, says Breast Cancer Now.
Meanwhile, roughly 300,000 new cases of invasive breast cancer are diagnosed in women every year in the US.